Jabberwock Island – once a popular tourist destination, this now uninhabited island remains oddly pristine. You and your classmates at the elite Hope's Peak Academy have been brought to this island by your super-cute teacher for a “lovey-dovey, heart-throbbing school trip.” Everyone seems to be having fun in the sun...until Monokuma returns to restart his murderous game! Trapped on this island of mutual killing, your only hope of escape rests in solving the island’s mysteries. But be warned—sometimes the truth can be its own despair...
To escape from this island, the Ultimate students of Hope’s Peak Academy must kill each other yet again. After the body discovery announcement, the students are given time to conduct an investigation. Afterward, a class trial will begin in order to identify the blackened killer.
During the investigation, you must gather clues about the murder by interviewing other students and examining objects. As the investigation progresses, you will obtain Truth Bullets—hints that will help you solve the case. These hints may range from physical evidence to students detailing their account of events.
During Free Time, you can choose a student to spend time with and get to know them better. By spending time with a student and giving them presents, you can learn their personal secrets and form a stronger bond with them. Presents can be obtaining either through the Monomono Yachine or vending machines.
You can use these machines once you’ve reached a certain point in the story. By spending Monocoins, you can obtain various presents. The Monomono Yachine dispenses different presents at random, while the vending machine allows you to spend set amounts of Monocoins to obtain specific presents.